The picturesque little town of Amalfi was once a major Mediterranean naval power, but a devastating earthquake in 1343 cut the city down in its prime and destroyed most of its historic buildings. These days, of course, Amalfi is best known for the eponymous stretch of stunning coastline on which it sits.

Situated on the western edge of Sicily, closer to Tunis than it is to Rome, the historic port of Trapani has a discernible North African feel to it. This was once an important medieval trading centre that linked Carthage and Venice, and the lovely old town is a great place to spend some time exploring.

Tunisia’s capital is a whirlwind of energy, the narrow lanes of the old medina packed with people and the roads noisy with traffic. The more orderly streets of the Ville Nouvelle are home to some handsome colonial buildings, while the ruins of ancient Carthage make for a fascinating day trip.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Rugged Kefalonia is the largest of the Ionian islands, and remains unspoilt by tourism despite earning fame as the setting for ‘Captain Corelli’s Mandolin’. The island rewards exploration, with some splendid beaches and lovely little villages, and the vineyards here produce some excellent wines.

The port of Brindisi sits at the end of the old Via Appia, and was once an important transit point for pilgrims and crusading knights heading east to the Holy Land. Brindisi's compact old town is pleasant enough, but you may prefer to head inland to visit the stunning baroque city of Lecce.

Kotor sits at the head of a beautiful, fjord-like bay, hemmed in by glowering mountains. The compact, walled old town is Montenegro’s star attraction, a warren of little alleyways and shady squares that is often described as a ‘mini Dubrovnik’.

We never fail to be moved when we see the terracotta roofs and honey-golden walls of Dubrovnik, and a stroll around the perfectly preserved old town is a highlight of any visit to the Dalmatian coast. Make sure you take the time to walk around the walls and soak up the marvellous sea views.

Croatia’s second city enjoys a dramatic setting, hugging a sweeping bay against a backdrop of sheer grey mountains. Split's labyrinthine old town is contained within the remarkable Roman ruins of Diocletian’s Palace, a UNESCO World Heritage Site, and spills out onto the buzzing seafront Riva promenade.

The largest town on Slovenia’s sliver of Adriatic coastline, Koper has an attractive medieval centre and some impressive Venetian architecture. There is also a sizeable Italian community here, reflected in the bilingual road signs, and it's a short drive across the border to the former Habsburg city of Trieste.