Busy, noisy and a little bit scruffy, Catania is Sicily’s second city, poised perilously in the shadow of Mount Etna. In recent years gentrification has taken hold, and the city’s many beautiful palazzi and baroque churches have been restored to their former glory. Eating out here is also a real treat.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Porto Empedocle, on the south west coast of Sicily, is the gateway to Agrigento and the UNESCO-listed Valley of the Temples. The temples are all that is left of the city of Akragas, one of the most impressive Ancient Greek sites outside of Greece itself.

Situated on the western edge of Sicily, closer to Tunis than it is to Rome, the historic port of Trapani has a discernible North African feel to it. This was once an important medieval trading centre that linked Carthage and Venice, and the lovely old town is a great place to spend some time exploring.

Lipari is the largest of the Aeolian Islands, a volcanic archipelago to the north of Sicily. The main port is Lipari Town, a charming little harbour of pastel-coloured houses, fishing boats and enticing restaurants, overlooked by the imposing 13th century citadel.

The lovely town of Sorrento, draped across rugged cliffs overlooking the Bay of Naples, has been charming visitors since the days of the Grand Tour. The Renaissance palaces and many craft shops make Sorrento an attractive destination in its own right, and it’s also a jumping off point for Capri, Pompeii and the Amalfi Coast.

The picturesque little town of Amalfi was once a major Mediterranean naval power, but a devastating earthquake in 1343 cut the city down in its prime and destroyed most of its historic buildings. These days, of course, Amalfi is best known for the eponymous stretch of stunning coastline on which it sits.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The island of Elba, just off the Tuscan coast, is where Napoleon Bonaparte was famously forced to live in exile between 1814-15. It’s hard to feel too sorry for him, though; the views from his plush Villa dei Mulini, situated high above the town of Portoferraio, are quite spectacular.

This tiny village on the Ligurian coast must be one of the most photographed spots in Italy, and no wonder; brightly coloured houses cling to the hillside overlooking a delightfully picturesque little harbour, where fishing boats gently bob alongside luxury yachts.

Renowned for its casino, its Grand Prix and its oligarch-friendly tax policies, Monte Carlo is glamour and hedonism personified, with a price tag to match. This little principality enjoys a lovely setting, the villas and penthouses tumbling down the hillside towards the sweeping blue expanse of the Mediterranean.

Few ports conjure up images of glitz and movie star glamour quite so readily as Cannes. May is when the glitterati roll into town for the Film Festival, but there’s still plenty to divert you the rest of the year, including the old quarter, Le Suquet, and the dazzling Croisette.

The pretty Provençal fishing village of Sanary-sur-Mer is an agreeable place to spend a day, with a clutch of historic buildings and a lively open-air market. Sanary also has a fine literary heritage, home to a number of exiled German writers during the 1930s, and it was here that Aldous Huxley wrote ‘Brave New World’.

The bustling fishing village of Palamós is one of the loveliest spots on the Costa Brava, surrounded by beautiful beaches and rugged coves. You can also use your stop here as a jumping off point for exploring nearby medieval villages, the historic city of Girona or the fantastic Salvador Dalí museum in Figueres.