The faded port town of Livorno serves as a gateway to Tuscany’s star attractions. Wonderful Florence, the cradle of the Renaissance, is resplendent with beautiful architecture and unrivalled artistic treasures, while nearby Pisa is of course famous for its precarious Leaning Tower.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The lovely town of Sorrento, draped across rugged cliffs overlooking the Bay of Naples, has been charming visitors since the days of the Grand Tour. The Renaissance palaces and many craft shops make Sorrento an attractive destination in its own right, and it’s also a jumping off point for Capri, Pompeii and the Amalfi Coast.

The volcanic island of Santorini (known officially as Thira) is one of the most spectacularly beautiful in the Mediterranean. The pretty village of Oia, with its whitewashed houses and windmills tumbling down the hillside, is particularly photogenic.

Sun-kissed Rhodes, the largest of the Dodecanese islands, is steeped in history; the medieval heart of Rhodes Town was once home to the crusading Knights of St John, and later fell to the Ottoman sultan Suleiman the Magnificent. The hillside village of Lindos, with its pretty whitewashed houses, is another highlight.

Antalya is the biggest and busiest city on the Turkish Riviera, though there’s more to this place than just roasting on a beach. The historic Kaleiçi district is full of lovingly restored Ottoman mansions, and top attractions include the superb collection of classical treasures at the Antalya Museum, with pieces from the nearby archaeological sites of Perge and Aspendos.

Bodrum is one of the trendiest destinations on Turkey’s Aegean coast, with plenty of private yachts bobbing alongside the traditional gulet boats in the harbour. Whitewashed buildings draped in bougainvillea give the town a Greek feel, overlooked by the imposing 15th century crusader castle.

Saint John is said to have written the Book of Revelations in a cave on Patmos, and today the spot is marked by the hillside Monastery of the Apocalypse. As well as spirituality, the island is known for its beaches and upmarket vibe, with a scattering of stylish restaurants and bars.