The down-to-earth port of Sète, sandwiched between the Mediterranean and the Etang de Thau lagoon, is a working town rather than a tourist hotspot, though the canals and colourful buildings have a certain charm. It’s also a great spot for a seafood lunch, and a visit to the nearby citadel of Carcassonne is a popular excursion.

The rumbustious port of Marseille often gets a bad press, but the city has been transformed in recent years, with a host of new cultural attractions. The vibrant Vieux Port remains at the heart of life in Marseille, however, and is the best place to begin your exploration of the city’s many historic sights.

Nice enjoys a marvellous setting on one of the most glorious stretches of the Côte d’Azur, the sweeping Bay of Angels, so it’s no wonder that tourists have been flocking here since the 19th century.

The faded port town of Livorno serves as a gateway to Tuscany’s star attractions. Wonderful Florence, the cradle of the Renaissance, is resplendent with beautiful architecture and unrivalled artistic treasures, while nearby Pisa is of course famous for its precarious Leaning Tower.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The UNESCO World Heritage-listed centre of Naples rewards exploration, and in addition to the many cultural treasures waiting to be unearthed Neapolitans are rightly proud of their food; this is where you’ll find the best pizza in Italy. The city also acts as a gateway to the fascinating remains of Pompeii and Herculaneum, and the beautiful Amalfi coast.

Situated on the north eastern tip of Sicily, so close to the Italian mainland you can almost touch it, Messina is the busy main entry point to the island. The city was flattened by an earthquake in 1908, and again by Allied bombing in 1943, so few historical sights remain, although the cathedral is one of Sicily’s most impressive.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.

Crete’s bustling capital is a modern and cosmopolitan city, where the island’s rich history isn’t immediately apparent. Take a closer look, however, and you’ll find a fantastic archaeological museum, along with remnants of Venetian fortifications and a lively seafront promenade, with plenty of nice outdoor cafés.

Sun-kissed Rhodes, the largest of the Dodecanese islands, is steeped in history; the medieval heart of Rhodes Town was once home to the crusading Knights of St John, and later fell to the Ottoman sultan Suleiman the Magnificent. The hillside village of Lindos, with its pretty whitewashed houses, is another highlight.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Çanakkale occupies a key strategic location guarding the Dardanelles, at the meeting point of the Aegean and the Sea of Marmara. This region of Turkey is full of historical interest, including the battlefields of the disastrous Gallipoli campaign and the ruins of ancient Troy.