Renowned for its food, its misty mornings and its vertiginous streets, cosmopolitan San Francisco is quite unlike any other American city. Highlights include the iconic Golden Gate Bridge, the delightful waterfront and the bohemian quarter of Haight Ashbury.

Los Angeles is an energetic, creative place with cultural riches to match any world city, home to Hollywood glamour, the iconic beaches of Venice and Santa Monica, and affluent, image-conscious Beverly Hills.

The sister towns of Cabo San Lucas and San José del Cabo sit at the tip of Mexico’s Baja California peninsula. The towns themselves are mostly given over to luxury hotels and boisterous nightlife, but the surrounding landscape is characterised by arid arroyos, bristly cacti and rocky coastal outcrops.

Situated on a peculiarly shaped peninsula on the Gulf of Nicoya, Puntarenas is a popular weekend beach destination for residents of Costa Rica’s capital, San José. The port itself is not pretty, but the beachfront Paseo de los Turistas is a nice place to relax with a drink or enjoy a seafood lunch.

Cartagena was founded by Spanish conquistadors in 1533, and the beautifully preserved centre is a real highlight of Colombia’s Caribbean coast. The walled old town, the Ciudad Amurallada, is a camera-friendly collection of cobbled streets and colourful, colonial-era buildings.

The tiny Dutch Caribbean island of Aruba, located just off the coast of Venezuela, lies outside of the hurricane belt, meaning it enjoys a largely dry climate, and boasts some of the best beaches in the region, if not the world.

Downtown Miami is a destination in its own right, with a host of world class galleries, but it's still Miami Beach that draws the biggest crowds. The Art Deco district around South Beach is very much back in vogue, with new restaurants, bars and luxury developments sprouting up all over the place.

Founded by the Spanish in 1521, Puerto Rico’s capital is the second oldest European settlement in the Americas. Modern San Juan is a bustling city, home to over a third of the island’s population, but the cobbled streets of the Old Town remain the biggest tourist draw.

Antigua is famously home to 365 beaches - one for every day of the year - and there is an undeniable allure to the many white sand coves dotted along the coast. The capital, St John's, is worth a look, but if you've got time to visit the south coast you'll find historic Nelson's Dockyard a lot more interesting.

Castries, Saint Lucia’s diminutive capital, is home to some interesting markets and colonial buildings. The island’s highlights are situated elsewhere, however, and we’d recommend either heading south towards Soufrière, where the iconic Piton mountains guard a beautiful bay, or north to the bars, restaurants and beaches of Rodney Bay.

There’s more to Barbados than just beaches; the delightful architecture of the old garrison in Bridgetown, the capital, is fully deserving of its UNESCO World Heritage status, and the island interior is littered with old sugar plantations and natural wonders such as Harrison’s Cave.

Philipsburg is the gateway to an intriguing little Caribbean island with a dual personality: the Dutch side, St. Maarten, is the livelier of the two, with shopping malls, casinos and more of a nightlife scene, while French-speaking St. Martin is a more refined (and more expensive) affair, with a laid-back, continental air and a host of exclusive resorts and restaurants.

Tortola is the largest and most populous of the British Virgin Islands, and the bustling port at Road Town is a magnet for sailors from around the world. The island is blessed with some gorgeous beaches and secluded coves, and it’s a great place for a spot of snorkelling.