Chalon-sur-Saône was once a key trading centre and port, situated at the meeting of Roman roads, the river Saône and several other inland waterways. The city’s distinguished history is reflected in its handsome buildings, and this is an excellent base from which to explore the southern Burgundy wine regions.

The little town of Mâcon lies on the west bank of the Saône, at the southern edge of Burgundy, and it’s a great base for sampling the region’s famous wines. A popular excursion is a trip to nearby Beaune, home to the magnificent medieval Hospices de Beaune and its prestigious wine estate.

Situated at the confluence of the Rhône and Saône rivers, Lyon is one of France’s most appealing cities. Its reputation for gastronomic excellence is well deserved, with hundred of wonderful restaurants, and the UNESCO listed historic centre boasts a marvellous ensemble of Renaissance-era buildings.

Vienne was an important trading centre during Roman times, and spectacular remnants of this era survive, including a remarkably well preserved temple and a hillside amphitheatre with marvellous views across the red-tiled rooftops. The city also hosts a renowned jazz festival during July, featuring some of the world’s most talented musicians.

The former papal stronghold of Avignon cuts a dramatic figure, perched above the Rhône and ensconced behind towering walls. The Palais des Papes was home to a succession of 14th century pontiffs, and still looms large over Avignon’s atmospheric old town.

The charming little town of Arles sits at the head of the Rhône delta, on the northern fringe of the sprawling marshlands of the Camargue. It’s a town with a long history, as evidenced by an impressive array of Roman ruins, and it's a great place to sample the essence of Provençal culture.

Few ports conjure up images of glitz and movie star glamour quite so readily as Cannes. May is when the glitterati roll into town for the Film Festival, but there’s still plenty to divert you the rest of the year, including the old quarter, Le Suquet, and the dazzling Croisette.