Delos was venerated by the Ancient Greeks as the birthplace of the gods Apollo and Artemis, and the sprawling ruins are now a UNESCO World Heritage Site. Delos sits at the centre of the Cyclades group, which take their name from the fact that they encircle the sacred island.

Glamorous Mykonos is the most popular of the Cyclades islands, well known as a haunt of the rich and the famous. It’s also the gateway to the nearby island of Delos, home to one of the most important archaeological sites in Greece.

Saint John is said to have written the Book of Revelations in a cave on Patmos, and today the spot is marked by the hillside Monastery of the Apocalypse. As well as spirituality, the island is known for its beaches and upmarket vibe, with a scattering of stylish restaurants and bars.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.

Kos is the second largest of the Dodecanese Islands after Rhodes, and is best known for its excellent beaches. There are plenty of cultural treasures here too: Kos Town’s harbour is guarded by an impressive castle built by the Knights of St John, and the island is scattered with Greek and Roman ruins.

The volcanic island of Santorini (known officially as Thira) is one of the most spectacularly beautiful in the Mediterranean. The pretty village of Oia, with its whitewashed houses and windmills tumbling down the hillside, is particularly photogenic.

Paros gleams with a classic Cycladic colour palette of whitewashed houses and blue-domed churches, and is famous for its ancient marble quarries, which provided the raw material for the Venus de Milo. The island is also home to some great restaurants, peaceful inland villages and lovely beaches.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.

The port of Itea, situated on the Greek mainland to the west of Athens, is the gateway to the magnificent ruins of Delphi. The spectacular cliffside setting at the foot of Mount Parnassos adds to the drama of this holiest of Ancient Greek sites, home to a famous oracle in antiquity.

Rugged Kefalonia is the largest of the Ionian islands, and remains unspoilt by tourism despite earning fame as the setting for ‘Captain Corelli’s Mandolin’. The island rewards exploration, with some splendid beaches and lovely little villages, and the vineyards here produce some excellent wines.

The charming Puglian town of Gallipoli lies close to the bottom of Italy’s ‘heel’, with the modern town on the mainland connected by bridge to the walled old town, which sits just offshore on its own island. The cobbled streets are a delight to explore, full of beautiful baroque palazzi and enticing seafood restaurants.

The charming village of Giardini Naxos is one of the jewels of Sicily, a popular resort located on a majestic bay facing the Ionian Sea. Restaurants and bars line a long stretch of beach, and the attractive town of Taormina is within easy reach, along with the slopes of brooding Mount Etna.

The captivating island of Capri has much to offer, from the ruins of Roman villas to gorgeous private residences surrounded by flower-filled gardens. You might also want to explore the famous Blue Grotto, with its intense azure interior and ethereal silvery light.

The lovely town of Sorrento, draped across rugged cliffs overlooking the Bay of Naples, has been charming visitors since the days of the Grand Tour. The Renaissance palaces and many craft shops make Sorrento an attractive destination in its own right, and it’s also a jumping off point for Capri, Pompeii and the Amalfi Coast.