Chania, Crete’s second city, is an alluring blend of architectural styles. The jumble of streets that make up the Venetian old town are remarkably intact, and there are plenty of reminders too of the two centuries of Ottoman rule, such as the imposing harbourfront Mosque of the Janissaries.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Palermo is an acquired taste; noisy, chaotic and rather grimey in places. But there’s something quite intoxicating about the crumbling facades and the bustling markets, and the Arabesque style of many of the buildings hints at Sicily’s historical role as a stepping stone between Europe and North Africa.

Spain’s third city is a dazzling destination that combines historic architecture, cutting edge design and an inviting stretch of beach. Don’t miss the futuristic City of Arts and Sciences, designed by local architect Santiago Calatrava, or the old riverbed, now a delightful park.