The crumbling, sun-baked seafront city of Cádiz is said to be the oldest continuously inhabited settlement in the western world, founded by the Phoenicians around 1100 BC. Although the city lacks any obvious landmarks, it’s rich in atmosphere, and plays host to one of Spain’s most colourful carnivals.

Málaga boasts plenty of chic restaurants and bars where you can ease into the rhythms of life in southern Spain, before exploring sights including the intriguing, unfinished Gothic cathedral, and a museum devoted to the city's most famous son, Pablo Picasso.

Cartagena was founded by the Carthaginians around 227 BC, who named it after their home city in North Africa. These days the city is best known for its well-preserved Roman theatre, which was remarkably only discovered in 1987, in spite of its location in the centre of town.

Spain’s third city is a dazzling destination that combines historic architecture, cutting edge design and an inviting stretch of beach. Don’t miss the futuristic City of Arts and Sciences, designed by local architect Santiago Calatrava, or the old riverbed, now a delightful park.

Malta’s tiny capital, established by the Knights of St John, packs in an awful lot of history considering its diminutive size. The atmospheric old streets, bathed in Mediterranean sunshine, are full of attractive honey-golden buildings, along with an impressive selection of bars and restaurants.

Chania, Crete’s second city, is an alluring blend of architectural styles. The jumble of streets that make up the Venetian old town are remarkably intact, and there are plenty of reminders too of the two centuries of Ottoman rule, such as the imposing harbourfront Mosque of the Janissaries.

Sun-kissed Rhodes, the largest of the Dodecanese islands, is steeped in history; the medieval heart of Rhodes Town was once home to the crusading Knights of St John, and later fell to the Ottoman sultan Suleiman the Magnificent. The hillside village of Lindos, with its pretty whitewashed houses, is another highlight.

The Turkish port of Kusadasi is the gateway to Ephesus, one of the most spectacular archaeological sites in the Eastern Mediterranean. This was the Roman capital of Asia Minor, and the remains constitute the most complete classical city in Europe.