Glamorous Mykonos is the most popular of the Cyclades islands, well known as a haunt of the rich and the famous. It’s also the gateway to the nearby island of Delos, home to one of the most important archaeological sites in Greece.

Saint John is said to have written the Book of Revelations in a cave on Patmos, and today the spot is marked by the hillside Monastery of the Apocalypse. As well as spirituality, the island is known for its beaches and upmarket vibe, with a scattering of stylish restaurants and bars.

The bustling port of Volos sits on the site of the ancient city of Iolkos, the mythological home of Jason and the Argonauts. The modern city has plenty of interesting museums and churches, along with a pleasant waterfront lined with restaurants.

Greece’s bustling second city has a rich history, shaped by Roman, Byzantine and Ottoman rule, and was once home to a large Jewish community. Sadly many of Thessaloniki’s historic buildings were destroyed by a fire in 1917, but the famous White Tower survives, along with the city’s vibrant, multicultural spirit.

Kavala has a rich history dating back nearly 3,000 years, and was known in antiquity as Neapolis. Many of the city’s most interesting sights were built by the Ottomans, including the aqueduct of Suleyman the Magnificent and the beautiful Imaret, a former religious school.

Istanbul is the place where East meets West, where Asia Minor reaches out across the Bosphorus and almost touches Europe, and the city remains a bristling, bustling cultural melting pot, the skyline dotted with magnificent minarets and domes.

Paros gleams with a classic Cycladic colour palette of whitewashed houses and blue-domed churches, and is famous for its ancient marble quarries, which provided the raw material for the Venus de Milo. The island is also home to some great restaurants, peaceful inland villages and lovely beaches.

Palermo is an acquired taste; noisy, chaotic and rather grimey in places. But there’s something quite intoxicating about the crumbling facades and the bustling markets, and the Arabesque style of many of the buildings hints at Sicily’s historical role as a stepping stone between Europe and North Africa.

The UNESCO World Heritage-listed centre of Naples rewards exploration, and in addition to the many cultural treasures waiting to be unearthed Neapolitans are rightly proud of their food; this is where you’ll find the best pizza in Italy. The city also acts as a gateway to the fascinating remains of Pompeii and Herculaneum, and the beautiful Amalfi coast.

Porto Santo Stefano sits on the slopes of Monte Argentario, a promontory connected to the Tuscan coast by three slender spits of land. The port was subjected to frequent pirate raids until the Spanish fortified it in the 16th century, and the fortress still looms over the harbour.