The rumbustious port of Marseille often gets a bad press, but the city has been transformed in recent years, with a host of new cultural attractions. The vibrant Vieux Port remains at the heart of life in Marseille, however, and is the best place to begin your exploration of the city’s many historic sights.

Renowned for its casino, its Grand Prix and its oligarch-friendly tax policies, Monte Carlo is glamour and hedonism personified, with a price tag to match. This little principality enjoys a lovely setting, the villas and penthouses tumbling down the hillside towards the sweeping blue expanse of the Mediterranean.

The faded port town of Livorno serves as a gateway to Tuscany’s star attractions. Wonderful Florence, the cradle of the Renaissance, is resplendent with beautiful architecture and unrivalled artistic treasures, while nearby Pisa is of course famous for its precarious Leaning Tower.

One of the world’s great cities, Rome continues to dazzle and delight visitors with a potent mix of architectural marvels, continent-defining history and buzzing nightlife. The Colosseum, the Vatican and the Forum are among the big ticket items, with the crowds to match, though in truth you will find history around almost every corner.

The lovely town of Sorrento, draped across rugged cliffs overlooking the Bay of Naples, has been charming visitors since the days of the Grand Tour. The Renaissance palaces and many craft shops make Sorrento an attractive destination in its own right, and it’s also a jumping off point for Capri, Pompeii and the Amalfi Coast.

Busy, noisy and a little bit scruffy, Catania is Sicily’s second city, poised perilously in the shadow of Mount Etna. In recent years gentrification has taken hold, and the city’s many beautiful palazzi and baroque churches have been restored to their former glory. Eating out here is also a real treat.

The Calabrian city of Crotone was once an important Greek colony, home to the mathematician Pythagoras, and some ruins still survive at Capo Colonna, to the south of the modern city. Another popular excursion is a visit to the fishing village of Le Castella, where a fairytale castle sits on an island at the end of a narrow causeway.

Kotor sits at the head of a beautiful, fjord-like bay, hemmed in by glowering mountains. The compact, walled old town is Montenegro’s star attraction, a warren of little alleyways and shady squares that is often described as a ‘mini Dubrovnik’.

The largest town on Slovenia’s sliver of Adriatic coastline, Koper has an attractive medieval centre and some impressive Venetian architecture. There is also a sizeable Italian community here, reflected in the bilingual road signs, and it's a short drive across the border to the former Habsburg city of Trieste.

Venice is a city like no other, a marble maze of turquoise canals criss-crossed by beautiful bridges, overflowing with palaces, churches and charming little piazzas. No matter how many times you’ve seen it in photographs, that first glimpse of the Grand Canal will simply take your breath away.

Located on the quieter northern stretch of Croatia’s Dalmatian coast, the walled port city of Zadar is an intriguing blend of old and new, where Roman ruins and psychedelic modern art installations sit alongside one another.

One of the Dalmatian coast’s lesser known cities, Šibenik is notable for its compact medieval centre, UNESCO-listed Gothic-Renaissance cathedral and crumbling fortresses. The nearby islands of Zlarin and Prvić also make for an enjoyable day trip.

Croatia’s second city enjoys a dramatic setting, hugging a sweeping bay against a backdrop of sheer grey mountains. Split's labyrinthine old town is contained within the remarkable Roman ruins of Diocletian’s Palace, a UNESCO World Heritage Site, and spills out onto the buzzing seafront Riva promenade.

Draped in vineyards and olive groves, the verdant Croatian island of Korcula is famous for its white wine and is said by some to be the birthplace of Marco Polo. The main settlement, Korcula Town, bears more than a passing resemblance to Dubrovnik, with a historic centre encircled by medieval walls and towers.

We never fail to be moved when we see the terracotta roofs and honey-golden walls of Dubrovnik, and a stroll around the perfectly preserved old town is a highlight of any visit to the Dalmatian coast. Make sure you take the time to walk around the walls and soak up the marvellous sea views.

Kotor sits at the head of a beautiful, fjord-like bay, hemmed in by glowering mountains. The compact, walled old town is Montenegro’s star attraction, a warren of little alleyways and shady squares that is often described as a ‘mini Dubrovnik’.

Chania, Crete’s second city, is an alluring blend of architectural styles. The jumble of streets that make up the Venetian old town are remarkably intact, and there are plenty of reminders too of the two centuries of Ottoman rule, such as the imposing harbourfront Mosque of the Janissaries.

Athens is a city awash with historical and cultural significance, but it's much more than an open air museum; this is a dynamic, bustling metropolis, and a place where history is still very much unfolding.

Istanbul is the place where East meets West, where Asia Minor reaches out across the Bosphorus and almost touches Europe, and the city remains a bristling, bustling cultural melting pot, the skyline dotted with magnificent minarets and domes.

Çanakkale occupies a key strategic location guarding the Dardanelles, at the meeting point of the Aegean and the Sea of Marmara. This region of Turkey is full of historical interest, including the battlefields of the disastrous Gallipoli campaign and the ruins of ancient Troy.

Greece’s bustling second city has a rich history, shaped by Roman, Byzantine and Ottoman rule, and was once home to a large Jewish community. Sadly many of Thessaloniki’s historic buildings were destroyed by a fire in 1917, but the famous White Tower survives, along with the city’s vibrant, multicultural spirit.

The bustling port of Volos sits on the site of the ancient city of Iolkos, the mythological home of Jason and the Argonauts. The modern city has plenty of interesting museums and churches, along with a pleasant waterfront lined with restaurants.

Syros is one of the smallest of the Cyclades islands, though it’s also the administrative capital of the archipelago. Not many cruise ships call here, so you’ll find the beaches are much less crowded than other islands, and the main town, Ermoupoli, is home to a fascinating mix of architectural styles.

Saint John is said to have written the Book of Revelations in a cave on Patmos, and today the spot is marked by the hillside Monastery of the Apocalypse. As well as spirituality, the island is known for its beaches and upmarket vibe, with a scattering of stylish restaurants and bars.

Nafplion is one of the most beautiful cities on the Greek mainland, situated on the Argolic Gulf overlooked by the imposing Palamidi Fortress. The narrow streets of the old town are home to a beguiling mix of Venetian, Turkish and Greek architecture, while just offshore is the little island castle of Bourtzi.